-
- WP-1 Méthodes et Instrumentations innovantes en radiothérapies
- WP-2 Techniques innovantes d'imagerie
- WP-3 Radiobiologie et modélisation pour les radiothérapies innovantes
- WP-4 Traitement d'images multidimensionnelles
- WP-5 Simulation et modélisation d'images
- Financement de la recherche
- Publications
- International
Vous êtes ici : Version française > Consortium > Equipes
-
Partager cette page
Unité de recherche
équipe BIORAN du Centre de Recherche en Neurosciences de Lyon
Our aims are to propose biochemical and radiopharmaceutical assays as brain biomarkers:
• to visualize and quantify pathophysiological targets in animal models and to contribute to transfer to patients;
• to propose innovative strategies to facilitate differential and early diagnostics;
• to accelerate the process from preclinical discovery to clinical phases.
Methods & Techniques
Molecular imaging: PET radiopharmacology and radiopharmacy, in vitro and in vivo animal imaging, neuropharmacology
Analytical neurochemistry and clinical biochemistry
Brain anatomopathology
Research projects
1. Receptors involved in cognition:
- New targets: serotonin 5-HT6, 5-HT7 receptors: from radiotracers to clinical phase I studies
- Functional 5-HT1A receptors: ligand/receptor interactions, functional mapping, endogenous 5-HT competition
2. Aggregated proteins involved in cognition:
- Biochemical and PET detection of α-synuclein
- Mechanisms of protein propagation
• to visualize and quantify pathophysiological targets in animal models and to contribute to transfer to patients;
• to propose innovative strategies to facilitate differential and early diagnostics;
• to accelerate the process from preclinical discovery to clinical phases.
Methods & Techniques
Molecular imaging: PET radiopharmacology and radiopharmacy, in vitro and in vivo animal imaging, neuropharmacology
Analytical neurochemistry and clinical biochemistry
Brain anatomopathology
Research projects
1. Receptors involved in cognition:
- New targets: serotonin 5-HT6, 5-HT7 receptors: from radiotracers to clinical phase I studies
- Functional 5-HT1A receptors: ligand/receptor interactions, functional mapping, endogenous 5-HT competition
2. Aggregated proteins involved in cognition:
- Biochemical and PET detection of α-synuclein
- Mechanisms of protein propagation
COORDONNÉES
- Adresse :
- BIORAN – Biomarqueurs radiopharmaceutiques et neurochimiques
Centre de Recherche en Neurosciences de Lyon Inserm U1028 - CNRS UMR5292 Groupement Hospitalier Est - CERMEP 59 bd Pinel
69677 Bron
Organisation
Responsable(s)
- Luc Zimmer ()
Composition de l'équipe
Permanents de l'équipe membres du LabEx Primes:Sandrine BOUVARD (IE Lyon 1)
Fabien CHAUVEAU (CR CNRS)
Sophie LANCELOT (MCU-PH Lyon 1/ HCL)
Géraldine PINA-JOMIR (MCU-PH Lyon 1/ HCL)
Mathieu VERDURAND IR HCL
Wael ZEINYEH (MCF Lyon 1)
Luc ZIMMER (PU-PH Lyon 1/ HCL)
Publications
Lien vers le site des publications de l'équipe
Structure(s) de rattachement :
Tutelle :
INSERM, CNRS, Lyon 1, UJM
Département :
Biologie, médecine, santé